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- The VBE can be caused by the damage of blood brain barrier (BBB). VBE的发生是血脑屏障(blood brain barrier, BBB)通透性增加的结果。
- A majority of blood brain barrier(BBB) was normal but some was destroyed. 血脑屏障(BBB)多数正常,部分被破坏;
- Aim To study the action of RMP-7 and its derivative on transporting liposome across the blood brain barrier (BBB) into the brain. 目的 研究RMP 7及其衍生物对脂质体跨血脑屏障的促进作用。
- AIM: To study whether efflux of glutamate (Glu) at blood brain barrier (BBB) was regulated by P-glycopro-tein(P-gp). 目的:研究血脑屏障(BBB)上谷氨酸(Glu)外排是否受P-糖蛋白(P-gp)调节。
- NP-SLE patients with local CNS involvements showed mainly the damage of blood brain barrier(BBB) . 相反,局限性CNS受损患者主要表现为血脑屏障(BBB)破坏。
- EB and CG were used to evaluate the permeability of the blood brain barrier(BBB) . 用伊文蓝 (EB)、胶体金 (CG)示踪血脑屏障 (BBB)通透性变化。
- Objective To investigate the changes of blood brain barrier (BBB) after severe craniocerebral trauma. 目的研究颅脑创伤后血脑屏障(BBB)的改变。
- Objective To explore the changes of blood brain barrier(BBB) permeability following acute altitude hypoxia exposures in rats. 目的 观察急性中、重度低压缺氧条件下 ,大鼠血脑屏障通透性的变化特点 ,为阐明低压缺氧作用下脑功能障碍的可能机理提供生理学依据。
- Objective To explore the dynamic changes of blood brain barrier(BBB)permeability after experimental subarachnoid hemorrhage(SAH)in rats. 目的探讨大鼠蛛网膜下腔出血(subarachnoid hemorrhage,SAH)后血脑屏障(blood brain barrier,BBB)通透性变化。
- Objective To explore the effect of thrombin on the permeability of blood brain barrier (BBB) and its possible mechanism. 目的 探讨凝血酶 (thrombin,TM)对血脑屏障 (blood brain barrier,BBB)通透性的影响及其可能机制。
- AIM: To construct 3D QSAR models of drugs passing through the blood brain barrier (BBB), that provide a theoretical basis for molecular drug design. 目的:建立药物透过血脑屏障的三维构效模型,为药物分子设计提供理论依据。
- Meanwhile we observe cerebral vascular endothelial cell ultrastructure alteration and situation of blood brain barrier (BBB). 同时对脑组织毛细血管内皮细胞超微结构进行观察,更直观的了解CO 中毒后脑血管内皮细胞的形态学变化,探究其对脑血液循环和血脑屏障(blood brain barrier, BBB)的影响。
- Aim To synthesize acylated prodrug of tacrine hydrochloride (THA) to improve the infiltration ability across the blood brain barrier (BBB). 目的 制备盐酸他克林 (THA)的酰化前体药物以提高其透过血脑屏障 (BBB)的能力。
- Purpose To identify the reliability and value of contrast enhanced MRI in monitoring the reversible blood brain barrier(BBB) opening. 目的评价增强MRI在监测可逆性血脑屏障(BBB)开放的可靠性及价值。
- In order to investigate the potential mechanism, we study the effect of PLA2 on the blood brain barrier(BBB)of rats by means of PLA2 and Evans blue(EB) injected intravascularly. 用伊文氏蓝(Evan'sBlue,EB)示踪,肉眼和切片观察脑组织EB蓝染情况,作为BBB通透性增高的一般指示剂。
- Objective To explore the dynamic changes of regional cerebral blood flow(rCBF) and blood brain barrier(BBB) in rats with experimental subarachnoid hemorrhage(SAH), and the effects of Nimodipine. 目的 探讨大鼠蛛网膜下腔出血 (SAH)后局部脑血流 (rCBF)与血脑屏障 (BBB)超微结构的动态变化规律和尼莫地平 (Nim)的作用特点。
- Objective To observe the local inflammatory response in injured rabbit brain and Blood Brain Barrier(BBB) permeability and traumatic cerebral edema suppressed by anti IL 8 monoclonal antibodies. 目的 观察抗IL 8单抗对兔脑损伤后脑内炎症反应的抑制作用 ,以及对血脑屏障通透性和创伤性脑水肿的影响 ,探讨颅脑损伤后继发性脑损害新的治疗方法。
- Ultrastructuralchanges of blood brain barrier in human severe head injury. 人类重型脑创伤时血脑屏障的超微结构改变。
- IGF-1 in the peripheral blood can enter the CNS through blood brain barrier. 外周血中的IGF-1 可以通过血脑屏障进入中枢神经系统。
- Methods At different time following thrombin was infused into ventricule, the permeability and the destroyed volume of blood brain barrier(BBB), water content and ion content were measured. 方法 在鼠脑室内注入凝血酶 ,于不同时间段测定丘脑组织的血脑屏障 (BBB)通透性、BBB破坏体积、水电解质含量 ,并以脑室内注入生理盐水和注入凝血酶后再注入水蛭素的动物为对照。