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And the drug entrapment efficiencies of different drug/albumin ratios were higher than ... 制得的微球载药量高,具有明显缓释作用。
The mean entrapment efficiencies determined by minicolumn centrifugation method or ultracentrifugation method were 94.3% and 97.9% respectively. 用微柱离心法和冷冻超速离心法测得该脂质体的平均包封率分别为94.;3%25和97
Methods To prepare matrine liposomes by passive loading method and avtive loading method,the entrapment efficiencies were determined by minicolumn centrifuge-UV method. 方法采用被动载药和主动载药制备脂质体,用微柱离心-紫外分光光度法测定脂质体包封率。
QT-SLN was spherelike and smooth/The mean diameter was 2173nm and the entrapment efficiency was 48.50%. 槲皮素固体膳质纳米粒为圆整的类球形实体粒子;平均粒径为2173nm;包封率为48.;50%25。
The entrapment efficiency in cationic liposomes was in the same range even if the drug loading was increased. 即使填充药量增加，带有阳离子的脂质体的包封率（仍处于相同范围）没有变化。
To prepare clindamycin phosphate liposome, and to determine the entrapment efficiency and particle diameter of it. 目的制备克林霉素磷酸酯脂质体并测定包封率及粒径。
AIM:To establish a method of determining the entrapment efficiency of bulleyaconitine A multivesicular liposomes. 目的:建立测定草乌甲素多囊脂质体包封率的方法。
OBJECTIVE To evaluate the quality of astragaloside liposome and determine its entrapment efficiency. 目的对黄芪皂苷脂质体进行质量评价,测定黄芪皂苷脂质体的包封率。
The volume ratio of oil and water(W_1/O) had the most evident effect on entrapment efficiency among thr... 第一水相的体积对微球的表面形态影响很大,第一水相的比例越大,会在微球的表面留下更多的孔隙结构。
Objective: To establish an HPLC method for the determination of entrapment efficiency of sinomenine liposomes. 目的:建立青藤碱脂质体包封率的测定方法。
Aim To prepare integerrimine (INT ) liposomes with high drug entrapment efficiency ( DEE ) and good stability and then make them into liposomal gel. 目的制备具有高包封率和良好稳定性的全缘千里光碱(INT)脂质体,并将其制成凝胶剂。
There are slight differences of content ,the entrapment efficiency and accelerated test between liposome and proliposome. 冻干前后脂质体的含量和包封率变化不大，离心加速试验的结果也没有明显区别。
The sustained release microsphere has relatively higher entrapment efficiency, drug-loading rate as well as remarkable sustained release function. 该缓释微球具有较好的包封率和载药量，以及明显的缓释作用。
The mean diameter of the prepared AmB-PBCA-NP was 94.38 nm; the mean entrapment efficiency of the particles was 82%; and the drug loading rate was 56.10%. AmB-PBCA-NP平均粒径94.;38 nm;平均包封率为82%25;载药量56
METHODS:Alprostadil liposome was prepared by instillation technique,and technical conditions were optimized with particle size and entrapment efficiency as indexes. 目的:对制备前列地尔脂质体的工艺条件进行优化。
Methods ATRA liposomes was prepared by reverse evaporating method and to determine the concentration and the entrapment efficiency of ATRA liposomes by HPLC. 方法采用逆相蒸发法制备全反式维甲酸脂质体,高效液相色谱法检测活性药物含量及包封率,并进行加速试验检测其初步稳定性。
HPLC method was established for the determination of the entrapment efficiency of the liposomes loaded with vincristine sulfate and mitoxantrone hydrochloride. 建立了HPLC法测定硫酸长春新碱和盐酸米托蒽醌复方脂质体的包封率。
Aim:To prepare wogonin liposomes with high entrapment efficiency(EE) and desirable size,and to study in vitro release of the liposomes and its pharmacokinetics in rats. 目的:制备包封率高且粒径适宜的汉黄芩素脂质体,考察其体外释放及大鼠体内药代动力学。
Conclusions Using film-sonication method can prepare liposome with high entrapment efficiency and uniform size distribution.There are no obvious difference between liposome and proliposome. 结论采用薄膜分散-超声法能够制备出包封率较高、粒径比较均匀的脂质体，经冷冻干燥后，其各项性质没有明显的变化。
ABSTRACT Objective To prepare capreomycin sulfate liposomes to develop a method for determining its drug content and entrapment efficiency and to study the release profile in vitro. 目的制备硫酸卷曲霉素脂质体，建立含量和包封率的测定方法，初步考察其体外释放规律。