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- The main obejective is to construct an efficiently expressive prokaryotic clone of the second immunodominant epitopes in HTV-1 gp41, detect its products and evaluate it in testing the anti-HTV-1 antibody. 本课题构建了HIV-1 SF2株跨膜蛋白gp41第二优势表位簇基因的原核高效表达克隆,初步检验该融合蛋白抗原性,探讨将其作为侯选多肽用于制备诊断试剂、检测HIV-1抗体的可能性; 并探讨提高原核表达的途径。
- Identification of a Common Immunodominant Epitope of Coxsackie B Virus Coat Protein VP1 With Synthetic Peptides 应用合成肽研究柯萨奇B病毒衣壳蛋白VP1的共同抗原表位
- Keywords HIV envelope protein GP41;gene expression;immunodominant epitope;viral envelope proteins; HIV包膜蛋白质GP41;基因表达;免疫优势表位;病毒融合蛋白质类;
- immunodominant epitope 优势免疫表位
- Keywords Plasmodium falciparum;Malaria vaccine;Monoclonal antibody;Immunodominant epitopes; 恶性疟原虫;疟疾疫苗;单克隆抗体;免疫显性表位;
- And use the epitope to study SLE. 并将其应用与SLE研究。
- Expression of chimeric antigen of HCV with multiple immunodominant epitopes in E. Coli and its application for serological tests 丙型肝炎病毒优势表位嵌合抗原在大肠杆菌中的表达及其在血清学检测中的应用
- immunodominant epitopes 免疫显性表位
- The epitope was analyzed within 34 HCV complete sequences in GenBank. 用T细胞增殖实验方法检测对这一表位的应答。
- The method based on expressed peptide for mapping epitope on viral prot... 实验表明,用基因工程表达的多肽筛选抗原表位的方法是可行的。
- These results suggested that A21 recognizes a conformational epitope mainly compassing ErbB2 subdomain I. 结果显示A21抗体主要识别ErbB2胞外区靠近N端I区的空间表位。
- The method based on expressed peptide for mapping epitope on viral protein was reliable and applicable. 实验表明,有基因工程表达的多肽筛选抗原表位的方法是可行的。
- Epitope based vaccine design is adopted and chemical method is used to synthesis target genes. 方法采用基于表位的疫苗设计方法,用化学合成的方法制备该种分子。
- Conclusion High level expression of epitope from HEV could be achieved by tandem repeats. 结论通过首位串联可以实现HEV线性表位较高效的表达。
- Results:The new gene encoding the antigen epitope of SARS-CoV S protein was designed and synthesized s... 结论:可以重新设计新基因产生新型候选重组疫苗。
- In the paper,the several efficient methods in research of B-cell epitope were summarized and discussed. 文章归纳总结了近年来用于B细胞抗原表位分析的几种常用方法。
- We suggested that HCMV-pp65 AA336-AA379 may contain pathogenic epitope to lupus prone animals. 我们推测在狼疮倾向的动物体内HCMV-pp65 AA336-AA379 可能为病原蛋白质之一。
- Objective:To analyze the efficiency of delivery for CD8+ T cell epitope by attenuated E. 目的:分析体外、体内重组减毒大肠杆菌运送真核表达的CD8+T细胞表位的效应。
- To study the common epitope between Lumbricus terrestris( Lt) and Schistosoma japonicum( Sj) by phage displayed technology. 目的采用噬菌体呈现技术,获得蚯蚓与血吸虫的共同表位。
- In the research, we have designed a triple hybrid clone, designated as BPO , that coexpresses the three immunodominant lipoyl domains of PDC-E2, BCOADC-E2 and OGDC-E2 from human souces. 本研究设计克隆表达了一抗原蛋白三联体,命名为BPO,它包含了M2抗体识别的人源BCOADC-E2、PDC-E2、OGDC-E2的抗原表位片断。