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- Objective: To compare the function of bone resorption by the multinucleated giant cell (MGC) separated from giant cell tumour(GCT) with the osteoclast. 目的：比较骨巨细胞瘤中的多核巨细胞与破骨细胞骨吸收的功能特点。
- Vitreous cytology revealed various cell types of lens-laden macrophage, lymphocyte and multinucleated giant cell. 玻璃体的细胞学检查，发现在吞噬细胞、淋巴球、以及多核巨细胞。
- Microscope, the cell density, shaped obviously, we can see strange single-core or multinucleated giant cells. 镜下，细胞密集，异型性明显，可见怪异单核或多核巨细胞。
- Objective To determine the origin and function of multinucleated giant cells and mononulear stroma cells in giant cell tumor of bone. 目的探讨骨巨细胞瘤中多核巨细胞和单核基质细胞的起源及在肿瘤中的作用。
- Histologically, giant cell tumors of bone as seen here are composed of multinucleated giant cells in a sea of round to oval mononuclear cells. 骨巨细胞瘤，是由大量圆形、卵圆形的单核基质细胞和分布于其间的多核巨细胞组成。
- Abstract： Objective To determine the origin and function of multinucleated giant cells and mononulear stroma cells in giant cell tumor of bone. 摘 要： 目的探讨骨巨细胞瘤中多核巨细胞和单核基质细胞的起源及在肿瘤中的作用。
- ADAM8, ADAM12 and CD68 positive signals were located in the cell membrane and cytoplasm of all multinucleated giant cells and some round mononuclear cells in the lesions. ADAM12和CD68在颌骨中心性巨细胞肉芽肿和长骨骨巨细胞瘤中几乎所有多核巨细胞和部分圆形单核基质细胞均为阳性。
- Results Multinucleated giant cells were mainly labeled by CD68, ACT,AACT and lysozyme, but were unlabeled by PCNA. 结果多核巨细胞主要表达CD68、AACT、ACT以及溶菌酶,无一表达PCNA;
- Cytologic examination shows benign appearing spindle cells, chondroid cells, multinucleated giant cells and calcified debris (Diagn Cytopathol 2001;24:336). 细胞学检查显示良性的梭形细胞、软骨样细胞、多核巨细胞以及钙化的碎屑。
- multinucleate giant cell 多核巨细胞
- RNA in situ hybridization demonstrated positive ADAM12 mRNA in 12 cases of the detected tumors. The ADAM 12 mRNA positive signal was localized in the cytoplasm of almost all multinucleated giant cells and mononuclear stromal cells. RNA原位杂交则显示 12例骨巨细胞瘤组织全部呈ADAM12阳性反应 ,并且位于几乎所有的多核巨细胞和单核基质细胞胞质中。
- A biopsy on the right nasolabial fold showed dermal granuloma formation around hair follicles, composed of lymphocytes, epithelioid histiocytes and occasional multinucleated giant cells. 病理下可见真皮内的毛囊旁有肉芽肿产生，内含淋巴球、表皮样组织细胞以及少数的多核巨大细胞。
- The multinucleated giant cells do not come from a proliferating population of cells but may be a fusion product of histocyte like cells which possibly derived from the mononuclear macrophage system. 单核基质细胞中的纤维母细胞型为肿瘤的主要增殖成分,可能来自间充质。
- Results A massive dermal infiltration composed of lymphocytes intermingled with numerous histiocytes and multinucleated giant cells was found.A few lymphocytes showed mild epidermotropism. 结果 在皮肤肿块内致密淋巴细胞、组织细胞和多核巨细胞浸润，少数淋巴细胞向表皮性。
- The results showed that the cells had classic characteristics of osteoclasts: multinucleated giant cells, staining positively for TRAP in cells, forming bone absorptive lacunae on the bone slices. 结果表明，直接分离的细胞具有典型的破骨细胞的形态特点：属多核大细胞，TRAP染色阳性，能在骨片表面形成吸收陷窝。
- Giant cell tumors are lytic on radiography. 骨巨细胞瘤放疗后可溶解。
- multinucleate giant cells 多核巨细胞
- Giant cell (temporal) arteritis is uncommon before age 50. 巨细胞动脉炎（颞动脉）在50岁以前较少见。
- Purpose:To research the radiodiagnosis of giant cell tumor of bone. 目的:探讨骨巨细胞瘤X线诊断。
- Frequent osteoclast-like giant cells are present. 常见破骨样巨细胞。
