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- However high (micromolar) concentrations of S100B have shown to be neurotoxic, participating in the physiology of neurodegenerative disorders. 因此,CSF和血液中S-100蛋白增高是中枢神经系统损伤特异和灵敏的生化标志。
- Prion diseases is a kind of infectious,sporadic or genetic neurodegenerative disorders in both humans and animals,including scrapie in sheep,BSE in cattle and CJD in humans. 朊病毒疾病是人和动物中的一种传染性、散发性和遗传性的神经退行性脑病。
- It is hoped that in the long term these formulations will be useful for the treatment of a range of brain diseases including brain tumours, stroke and neurodegenerative disorders. 从长远观点来看,希望这些配方可以帮助治疗一系列的脑部疾病,包括脑肿瘤、脑卒中和神经退化失调。
- Several of the demonstrated inflammatory mechanisms are shared by other neurodegenerative disorders but some Parkinson's disease-specific mechanisms have also emerged. 有些炎症机制是与其他神经变性疾病共有的,但是也发现了一些帕金森氏病特异的机制。
- The neuronal ceroid lipofuscinoses (NCLs) are progressive, fatal neurodegenerative disorders of unknown pathogenesis with onset ranging from infancy to adulthood. 神经元蜡样脂褐质沉积症(NCL)是一些进行性致命的神经变性紊乱,其病原机理未知,发病年龄从婴儿期到成年期不等。
- The eukaryotic regulating expression system Tet-Off has Potentiality in gene therapy on the neurodegenerative disorders of CNS, such as AD, when using hNT-3 or other genes. 在应用hNT-3进行AD等中枢神经退行性疾病的基因治疗中,Tet-off调控表达系统具有潜在的应用前景。
- Any drug development effort to combat neurodegenerative disorders will have to examine carefully whether such pivotal signaling molecules adversely affect untargeted cell populations. 任何对抗神经退化的新药物,其发展都必须经过仔细的检验,以确定这些重要的讯息分子不会对不属于目标的诸多细胞造成不良的影响。
- Traumatic spinal cord injury (SCI) and neurodegenerative disorders affects many people, and can result in severe damage, leading to neuronal loss, paraplegia, tetraplegia, or worse. 如果能向患者患病的相应部位补充运动神经元,则患者就有治愈的希望。
- "You need to understand the fundamental mechanisms.Then you can gain better insight into what might go wrong during neurodevelopmental and neurodegenerative disorders," Svoboda said. 我们需要先理解正常生理状态下的基本的机制,然后才能更好的理解神经发育与神经退化等病态生理病理状态下的机制。
- Creutzfeldt-Jakob disease(CJD)is an incurable fatal neurodegenerative disorder resulting from transmissible spongiform encephalopathies(TSE). 克-雅病(CJD)是由传播性海绵状脑病引起的不可治愈的致命性神经退行疾病。
- Leigh syndrome is a severe early-onset progressive neurodegenerative disorder due to mitochondrial oxidative phosphorylation defects. Leigh综合征是一种由于线粒体氧化磷酸化障碍所导致的严重退行性脑病。
- Mad cow disease,or bovine spongiform encephalopathy(BSE),is a chronic,transmissible,fatal neurodegenerative disorder disease in cattle. 疯牛病(mad cow disease),即牛传染性海绵状脑病(bovine transmissible spongiform encephalopathy,BSE)的俗称,是一种慢性消耗性、致死性、中枢神经系统退行性疾病。
- Amyotrophic lateral sclerosis(ALS)is a fatal neurodegenerative disorder characterized by progressive loss of motoneurons. 肌萎缩侧索硬化(ALS)是一种运动神经元的进行性变性疾病。
- Abstract: Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder that affects about 1.7 million people in China . 摘要:帕金森病是一种慢性进展性的神经系统变性疾病,在我国有1.;7万左右的患者。
- Parkinson's disease is a neurodegenerative disorder which is caused by the death of dopaminergic neurons in the compact part of nigra. 摘要帕金森病是黑质多巴胺能神经元变性坏死而引起的神经系统退行性疾病。
- Batten disease is a rare, fatal, inherited disease of the nervous system (neurodegenerative disorder) that begins in childhood. 什麽是'巴滕疾病-遗传性神经系统建设的条件造成体细胞色素'?
- Amyotrophic lateral sclerosis (ALS)is a fatal neurodegenerative disorder characterized by progressive loss of motoneurons. 摘要肌萎缩侧索硬化(ALS)是一种运动神经元的进行性变性疾病。
- Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of dopaminergic neurons in the substantia nigra. 帕金森氏病(PD)是一种神经退行性疾病,其特征为黑质的多巴胺能神经元变性。
- Parkinson s disease(PD),is a progressively neurodegenerative disorder,resulting from the degeneration and loss of dopaminergic neurons in the substantia nigra of midbrain. 帕金森病是一种以中脑黑质多巴胺能神经元变性缺失为主要病理变化的渐进性神经系统退行性疾病。
- Alzheimer disease(AD) is a neurodegenerative disorder of the central nervous system.It is recognized as a major public health problem having a severe impact on human beings. 老年痴呆症是中枢神经退化性疾病,被认为是危害人类健康的一大综合症。