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The degeneration and disappear of dopaminergic neurons in the substantia nigra pars compacta induces the functional disorder of the efferent nuclei in basal ganglia circuity. 该病是由基底节黑质致密部多巴胺（dopamine，DA）能神经元的变性缺失导致该运动调控环路传出核团功能亢进而引起的。
Parkinson's disease (PD) is a neurodegenerative disorder characterized by a preferential loss of the dopaminergic neurons of the substantia nigra pars compacta, and the etiology is unknown. 帕金森病为中枢老年退行性疾病,发病原因尚未阐明。6-OHDA、多巴胺(DA)和MPTP(MPP+)为DA能神经元相对选择性神经毒物质。
Keywords Iptakalim hydrochloride;ATP-sensitive potassium channel;Substantia nigra pars compacta;Dopaminergic neuron;Nicotinic acetylcholine receptor;Patch clamp;Microdialysis; 盐酸埃他卡林;ATP敏感性钾通道;黑质致密部;多巴胺神经元;烟碱乙酰胆碱受体;膜片钳;微透析;
substantia nigra pars compacta 中脑黑质致密带
Keywords magnetic resonance imaging;Parkin son s disease;pars compacta of substantia nigra; 磁共振成像;帕金森病;黑质致密带;
Keywords MRI Parkinson s disease Vascular parkinsonism Pars compacta of substantia nigra; 关键词磁共振;帕金森病;血管性帕金森综合征;黑质致密带;
substantia nigra pars reticulata 黑质下网状部分
Keywords Parkinson's disease;magnetic resonance imaging;iron;oxidative stress;transverse relaxation time;pars compacta of substantia nigra;putamen;magnetic resonance spectroscopy; 帕金森病;磁共振成像;铁;氧化应激;横向驰豫时间;黑质;壳核;磁共振波谱;
EFFECT OF GABAB RECEPTOR ACTIVATION IN RAT SUBSTANTIA NIGRA PARS RETICULATA ON THE RAT ROTATIONAL BEHAVIOR 黑质网状带GABAB受体对大鼠运动行为的影响
substantia nigra pars eompaeta 黑质致密带
In conscious curarized and artificially ventilated rat, electrical stimulation ofthe zona compacta (SNc) or zona reticulata substantia nigra (SN_R) markedlysuppressed spontaneous unit discharges of the nucleus raphe magnus. 本工作观察到在清醒、麻痹大鼠,电刺激黑质致密部(SN_C)或网状部(SN_R)均明显抑制中缝大核(NRM)神经元的自发放电;
substantia nigra zona compacta, SNc 黑质致密带
It is believed to be jump-started by a loss of neurons in a midbrain region called the substantia nigra. 相信这是可以跳开始，由一个亏损的神经元在中脑区称为黑质。
The disease affects a small area of cells in the middle of the brain called the substantia nigra. 该疾病侵袭大脑中部一小部分被称为黑质的脑细胞。
Many GABA-like positive fibres were observed at the inferior colliculus level of substantia nigra. 在下丘平面还可见到许多GABA样阳性神经纤维。
No correlations were found in the volumes of the caudate, putamen, globus pallidus, substantia nigra with H&Y range. 结论：PD病人壳核体积大小与疾病严重程度呈负相关。
It is caused by the death of nerve cells in a midbrain area called substantia nigra. 它是由于中脑塞梅林氏神经节中的神经细胞死亡导致的。
Conclusions Passive smoking can partially protect DA neurons of substantia nigra from the damage of 6-OHDA. 结论被动吸烟可减轻6-OHDA对黑质DA能神经元的损伤。
Parkinson's disease (PD) is a neurologic disorder characterized by dopaminergic cell death in the substantia nigra. 帕金森氏病（PD）是一种以黑质多巴胺能细胞死亡为特征的神经疾病。
Conclusion Passive smoking can protect DA neurons of substantia nigra from the damage of 6-OHDA. 结论被动吸烟能减轻黑质纹状体DA能神经元的损伤。