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Objective To study the expression and significance of osteoprotegerin(OPG)in the development of dogs permanent teeth germs. 目的:探讨犬乳恒牙替换过程中骨保护素在犬恒牙胚发育中的表达及意义。
It is thought that tooth germs, dental papilla, dental pulp, and even pulp of exfoliated deciduous teeth have precursor cells which can form tooth. 牙胚、牙乳头、牙髓,甚至脱落的乳牙牙髓里都存在形成牙齿的前体细胞。
It was observed that the grow rate of pharyngeal bone would affect the formation of tooth germs. 本文还探讨了咽骨的发育及其对下咽齿发生的影响。
Objective: To study expression of whether Shh and its receptor Ptc during late bell stage in mouse tooth germ. 目的 :判断sonichedgehog(Shh)基因及其受体patched(Ptc)是否在小鼠牙胚钟状晚期有表达。方法 :用RT PCR法研究Shh及其受体Ptc在小鼠牙胚钟状晚期的表达。
Shh and its receptor are expressed during the late bell stage of mouse tooth germ. Shh及其受体Ptc在小鼠牙胚钟状晚期有表达。
Objective:To find a suitable growing environment for the bioengineered teeth in vivo by observing the development of rat tooth germs (rTGs) of heterotopic allotransplantation. 目的:观察牙胚在同种异体大鼠体内不同部位的发育情况,为进一步组织工程化牙齿的构建探寻合适的体内生长环境。
We infer that the minimum toxic dose should be below 10mg/L in cultured human tooth germ in vitro . 因此推断，在人牙胚体外培养中，氟产生毒性作用的最小剂量应低于10mg/L。
AIM: To observe the expression of GDNF in tooth germ and dental papillae mesenchymal cells. 目的:观察胶质源性神经营养因子(GDNF)在人牙胚和体外培养的人牙乳头间充质细胞中表达部位及其表达变化。
"Our reconstituted tooth germ generates a complete and entirely bioengineered tooth," theywrote. 研究人员在文章中说：“经过我们再生的牙菌长成了完全的和完整的生物工程牙齿。”
"Our reconstituted tooth germ generates a complete and entirely bioengineered tooth," they wrote. 他们认为“我们的再造牙胚能形成一个完整生物工程牙。”
AIM: To study the expression of Msx2 and BMP-4 in the cap stage of the mouse tooth germ and the relation with the mouse tooth morphogenesis. 目的 :探讨Msx2、BMP - 4基因在小鼠牙胚发育帽状期的表达及其与牙胚形态发育的关系。
METHODS: The expression patterns of Msx2 and BMP-4 in the cap stage of the mouse tooth germ were studied by in situ hybridization. 方法 :利用原位杂交的方法观察小鼠牙胚帽状期Msx2、BMP - 4基因的表达方式 ;
BMP may also be found in human tooth germs, predentin, the cells of outer and inner enamel epithelium, and the cells of dental sac generating alveolar bone. 在人的牙胚中,BMP主要分布在前期牙木质、外釉细胞和造釉细胞以及形成牙槽骨的牙囊细胞中,表明骨的生长和形成以及牙齿的发育都与BMR密切相关。
In this case the cells weretaken from what is known as the tooth germ, the little bud that appears before an animalgrows a tooth. 这样，所有的细胞都是从已知的牙菌中提取。牙菌是在动物长出牙齿之前所出现的小蓓蕾。
The developing bone trabeculae invaded the dental follicle and reached the molar tooth germs, provoking deformities in enamel surfaces.No root formation was observed. 发育中的骨小梁侵入牙囊接触到了牙胚导致釉质发育的障碍。
Method: bFGF expression was exmined with immmunohistochemical technique in bud stage,cap stage and bell stage of human tooth germ from aborted embryo of 7,8,10 and 14 weeks. 方法 :选择胎龄分别为 7、8、10、14周自愿终止妊娠的新鲜人胚胎各 4例 ,制作牙胚切片 ,将蕾状期、帽状期和钟状期牙胚切片 ,做免疫组化检测。
These results suggested that even when embryonic tooth germs are dissociated, the single cells can reconstitute tooth, and that enamel organ morphogenesis proceeds as in natural teeth. 本研究显示胚胎的牙胚细胞解离后，单个细胞同样具有形成牙齿的能力，重组后釉质的发育模式与正常牙齿相同。
In cultured primordia, molar and incisor tooth germs can easily be distinguished by their appearance and their gene activity, although other shapes found in the human mouth, such as premolars and canines, are more difficult. 在组织培养的牙齿原基里头，可以从外观和基因的活性，轻易分辨出臼齿与门齿的牙胚，不过，人类口腔里的其他牙齿，像是前臼齿与犬齿，就比较难以区分。
Total RNA from extracted tooth germs was reverse-transcribed to generate cDNA probes and then hybridized with the mouse gene expression Microarray CSC-ME-80, and results were analyzed using the MIDAS software from chipsreen bioscienses ltd. 从小鼠第一磨牙牙胚提取总RNA;反转录得到cDNA探针;与小鼠基因表达谱芯片CSC-ME-80进行杂交;使用软件MIDAS分析芯片实验数据.
Up to cap stage, bell stage and tooth tissue secretory stage, the expression of OPN was wider and more extensive than that of BSP. Especially during tooth tissue secretory stage, OPN was strongly positive in all tooth germ cells and bones. 在帽状期、钟状期及牙体硬组织(牙冠、牙根)分泌形成期,OPN的表达范围及强度高于BSP,尤其在牙体硬组织形成期,OPN在牙胚各类细胞及骨组织中均呈强阳性表达。