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- The binding between these ligands and receptors promotes the adhesion of cells.Polyethyleneglycol (PEG) can resist cell adhesion. 聚乙二醇（PEG）可以抵抗细胞在表面的黏附，我们利用含有PEG的表面小分子来调节细胞黏附。
- Vincristine could affect the activity of p38 MAPK in gastric cancer cell SGC7901 and multidrug resistant cell SGC7901/VCR. p38MAPK信号转导途径可能与长春新碱的抗肿瘤活性相关 ,肿瘤细胞内 p38MAPK对长春新碱刺激的反应速度可能与胃癌长春新碱耐药相关
- Objective To study drug resistant mechanism and reversal of glioma we established C 6 MDR drug resistant cell line(C 6/adr). 目的 为研究脑胶质瘤的耐药、机理及逆转 ,建立了C6耐阿霉素细胞株 (C6/adr)MDR细胞系。
- The effects of saponins Rb1 on the intracellular concentration of DNR in human leukemic multi-drug resistant cell K562/HHT in vitro. 人参皂甙单体Rb1对多药耐药细胞系K562/HHT细胞内柔红霉素浓度的影响
- Methods A resistant cell line-HT29/L-OHP was established by gradually increasing the dose of L-OHP and intermittent administration. 方法 采用逐步递增L-OHP浓度，间歇作用体外诱导法培养建立了人结肠癌L-OHP 耐药细胞模型HT29/L-OHP。
- Objective To explore the effects of saponins Rb1 on the intracellular concentration of DNR in human leukemic multi-drug resistant cell K562/HHT in vitro. 目的 探讨中药钙离子通道拮抗剂人参皂甙单体Rb1对白血病多药耐药细胞系 (K562 /HHT)细胞内柔红霉素浓度的影响。
- The chemosensitivity of multidrug resistant cell MCF-7Adr and drug sensitive cell MCF-7WTto doxorubicin,vincristine and colchicine was tested by MTT assay. 用MTT方法测定了多药抗药细胞MCF－7Adr及其敏感细胞MCF－7WT对阿霉素、长春新碱、秋水仙碱的化学敏感性。
- Flow cytometry was used to detect theexpression of HLA-l, HLA-2, B7-l, B7-2 in parent cell lines (COC1 andSKOV3 ) and multidrug resistant cell sublines (COCI/DDP andSKOV3/Adr). 运用流式细胞仪技术检测了各种不同细胞亚株的HLA-1、HLA-2、B7-1、B7-2的表达。 结果：耐药亚株COC1/DDP、SKOV_3/Adr和亲本株COC1、SKOV_3的N-GSLs表达有差异，COC1/DDP、SKOV_3/Adr的CMH表达较COC1、SKOV_3强。
- Objective To investigate the restoration of the subcellular distribution of daunorubicin in the P glycoprotein mediated multidrug resistant cell line K562/ADR by quercetin. 目的研究槲皮素处理前后柔红霉素(DNR)在耐药细胞株K562/ADR亚细胞结构的不同分布。
- Objective: To investigate the inhibitory effect of ampelopsin (AMP) combined with adriamycin (ADR) on growth of human leukemia multidrug resistant cell line K562/ADR. 目的：研究蛇葡萄素与阿霉素合用对人白血病多药耐药细胞株K562/ADR增殖的抑制作用及其机制。
- Bromodeoxyuridine resistant cells are obtained by a similar procedure. 用同样的处理方法，得到溴脱氧尿甙抗性细胞。
- Objective To explore the reversal effect of cyclosporin A(CsA) in combination with cytokines on multidrug resistant cell line K562/A02. Method The cytotoxicities of daunorubicin(DNR) were assayed by MTT method. 目的探讨环孢菌素A（CsA）联合细胞因子对耐药细胞系K562/A02的逆转作用。 方法以甲基四唑蓝法测定柔红霉素（DNR）的细胞毒性；
- Objective:The study was designed to examine the expressions of vascular endothelial growth factor C(VEGF C) mRNA and protein in human breast cancer cell line MCF 7 and drug resistant cell line MCF 7/Adr. 目的 :检测血管内皮生长因子C(vascularendothelialgrowthfactorC ,VEGF C)mRNA和蛋白在人乳腺癌细胞株MCF 7及其耐药株MCF 7/Adr中的定位、定性表达。
- Using such a common transporter to ferry a potent medication inside a resistant cell is a bit like recruiting your grandmother to cart a load of switchblade knives through customs. 利用这一常见的载体将有效的药物运送至耐药细胞中，这有点像让你的祖母装一车开关闸刀通过海关。
- Presumably poliovirus was incorporated into the resistant cells during the fusion process. 据推测，脊髓灰质炎病毒是在融合过程中渗入到耐受细胞内的。
- Conclusion A multidrug resistance cell line (SPC-A-1/CDDP) from human lung adenocarcinoma is established.It can be used to downstream experiment. 结论本研究建立了稳定的人肺腺癌多药耐药细胞系（SPC-A-1/CDDP），可应用于下游实验。
- Tetrandrine, neferine and dauricine showed obvious potenitiation of vincristine induced apoptosis in the human mammary MCF 7 multidrug resistant cells. 粉防己碱、甲基莲心碱和蝙蝠葛碱均有明显的增强长春新碱诱导人乳腺癌MCF 7多药耐药细胞的凋亡作用
- Methods Human myeloid leukemia cells, K562 and NB4, were transduced by MDR retrovirus and the resistant cells were selected. 方法用MDR病毒转导人类白血病细胞K562和NB4，获得耐药细胞系；
- AIM and METHODS: Matrine (50mg/L) potentiated the cytotoxicity of daunorubicin (DNR) in human leukemia multidrug resistance cell line K562/A02 by MTT assay. 方法和结果：经MTT法发现苦参碱50mg/L能增加K562/A02对柔红霉素的敏感性，使柔红霉素半数抑制浓度（IC50）由14?92mg/L降至8?29mg/L，部分逆转了K562/A02对柔红霉素耐药性，逆转倍数为1?80倍。
- The nobility usually resist social changes. 贵族通常反对社会变革。
