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- The researchers began by removing two genes from a vaccinia virus that are necessary for its growth in normal cells. 研究人员们首先将痘苗病毒中在正常细胞中生长所必须的两个基因去除。
- CB could be expressed in high yield by vaccinia virus eukaryotic expression system. 痘苗病毒真核表达系统可以高效表达目的蛋白。
- Results The recombinant vaccinia virus bearing CD19 gene was found to express on the surface of TK- 143 cells. 结果 含人 CD19基因的重组痘苗病毒可表达在TK-143真核细胞的表面。
- After spreading unchecked throughout the skin, the vaccinia virus can cause scarring, blindness, and even death. 如未予以治疗,湿疹发展至全身皮肤,则牛痘病毒会引起疤痕、失明甚至死亡。
- Among the leading candidates: the vaccinia virus that successfully wiped out smallpox. 最理想的对象包括当年成功扑灭天花的疫苗病毒。
- Vaccinia virus B1R gene product acts as protein kinase with an essential role in viral DNA replication. 牛痘病毒B1R基因产物是一个蛋白激酶,在病毒的DNA复制中起着重要作用。
- In this study,the mammalian condon optimized F gene was synthesized by over-lapping PCR and used to generate recombinant vaccinia virus,rWR-NiV-F. 通过over-lapping PCR合成密码子优化的F蛋白基因构建了表达NiV F蛋白的重组牛痘病毒(WR株)rWR-NiV-F。
- The human vaccinia virus B1R kinase related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein. 人类牛痘病毒B1R激酶相关激酶VRK1可使肿瘤抑制蛋白p53的Ser18磷酸化,该位点正是mdm-2的结合位点。
- Jennerex Biotherapeutics has presented positive results from a Phase I and II trial of a genetically-engineered vaccinia virus strain that is suited to treat cancers. 提示:欢迎您来到肝宝宝乙肝论坛,您目前的身份是游客,所以只能阅读部份内容。
- Schmaljohn CS,Chu YK,Schmaljohn AL,et al.Antigenic subunits of hantaan virus expressed by baculovirus and vaccinia virus recombinants[J].J Virol,1990,64:3162. 尹文;徐志凯;阎岩;等.;汉坦病毒S基因的分段表达及表达产物的鉴定[J]
- Immunization of rabbits with a recombinant vaccinia virus J 3 containing PrM,E,NS1, NS2A genes of japanese encephalitis virus(JEV) could produce rapidly specific antisera against JEV and the titres of antibodies increased with immunization times. 用含有日本脑炎病毒(JEV)结构蛋白PrM、E和非结构蛋白NS1、NS2A基因的重组痘苗病毒J3免疫家兔,能较快地诱生抗JEV抗体,其滴度可随免疫次数的增加和免疫时间的延长而增高。
- And the international AIDS pandemic vaccine design and technology very different routes, China's ongoing clinical trials is replicating vaccinia virus vector, belonging to the vaccine. 与国际上流行的艾滋病疫苗设计理念和技术路线大不相同,中国正在进行临床试验的是复制型痘苗病毒载体,属于活疫苗。
- Construction of Vaccinia Virus Vector for Vaccine Screening 适用于疫苗株筛选的痘苗病毒载体的构建
- Establishment of detection methods for vaccinia virus 痘苗病毒检测方法的建立
- Study on the infectivity of vaccinia virus in equine cells 痘苗病毒对马属动物细胞的感染性研究
- Extracts from Rabbit Skin Inflamed by Vaccinia Virus 牛痘疫苗致炎兔皮提取物
- Keywords Vaccinia virus;Immunogen;Recombinant plasmid;AIDS; 痘苗病毒;免疫原;重组质粒;艾滋病;
- Keywords vaccinia virus;green fluorescent protein;flow cytometer; 重组痘苗病毒;绿色荧光蛋白;流式细胞仪;
- A main feature of computer virus. 计算机病毒的一种主要特性。
- Keywords vaccinia virus;codon usage;correspondence analysis; 痘苗;密码子使用;对应分析;