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- FLT3/ITD突变Flt-3/ITD mutation
- 方法采用基因组PCR及RT-PCR方法检测126例AML患者的FLT3/ITD突变。Methods Reverse transcription polymerase chain reaction (RT-PCR) and genomic PCR were applied to monitor FLT3/ITD mutation in 126 AML patients.
- 伴有染色体易位且FLT3/ITD突变的急性髓性白血病患者预后较差,染色体易位和FLT3/ITD突变可以作为其预后不良的重要标志。The prognosis is relatively poor in FLT3/ITD mutation patients with chromosome translocation. FLT3/ITD mutation with chromosome translocation may be an important marker for poor prognosis of AML.
- Flt-3／ITD突变Flt-3/ITD mutation
- FLT3/ITD阳性AML患者早期死亡率高,FLT3/ITD阳性M3患者预后差,FLT3/ITD突变检测对于AML患者疗效评价、预后估计具有重要意义。FLT3/ITD was associated with a higher early case fatality rate in AML patients and a poor prognostic in APL patients. The detection of FLT3/ITD mutation will be valuable in therapeutic efficacy evaluation and prognostic assessment in AML patients.
- FLT3-ITDFLT3-ITD
- Flt3配体Flt3 ligand
- FLT3基因FLT3 gene
- ITD模态识别ITD modal identification
- FLT3内部串联复制FLT internal tandem duplication
- 油底壳模态参数识别ITD法The Identification of Modal Parameters of the Oil pan with ITD Algorithm
- 突变表型mutant phenotype
- 天气突变。There was a sudden change in the weather.
- 腺病毒介导的Flt3配体小鼠肝癌治疗研究Flt3 Ligand gene therapy of murine liver cancer mediated by recombinant adenovirus vector
- 在M3患者中,FLT3/ITD阳性者完全缓解率低(P=0.015)。The CR rate was lower in acute promyelocytic leukemia (APL) patients with FLT3/ITD (P=0.015).
- ｔｓ突变体temperature-sensitive mutant
- DIG掺入PCR半定量检测AML中Flt3基因的表达THE EXPRESSION OF FLT3 GENE IN AML DETECTED BY SEMI-QUANTITATIVE RT-PCR WITH INCORPORATION OF DIG
- 珠江水系广州河段水体中有机污染物的GC/ITD/COM联用法分析GC/ITD/COM Combined Analysis of Organic Pollutants in Guangzhou Urban Section of Pearl River Water System
- 半致死突变semilethal mutation
- THP-1、HL-60是FLT3野生型过表达的AML细胞株。THP-1 and HL-60 are AML cell lines with wild-type FLT3 receptor but over-express it in mRNA and protein levels.
