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- K562/A02细胞株K562/A02 cell line
- 目的:初步研究逆转剂汉防己甲素(Tet)和屈洛昔芬(DRL)对K 562/A02细胞株凋亡相关因子bcr/abl mRNA及蛋白表达的影响。Objective To observe the effect of Tetrandrine in combination with Droloxifen on the expression of bcr/abl mRNA and P~(210) BCR/ABL protein of K562/A02 cell line.
- K562/A02细胞K562/A02 cell
- 细胞cell
- K562/A02人白血病细胞株Human leukemia cell line K562/A02
- K562/A02细胞K562/A02 cell
- 细胞株cell strain
- 汉防己甲素联合屈洛昔芬对K562/A02细胞bcr/abl表达的影响Effect of Tetrandrine in Combination With Droloxifen on the Expression of bcr/abl mRNA and Protein of K562/A02
- 人淋巴因子激活的杀伤细胞对肝癌细胞株凋谢作用的观察A Observaion of Apoptoisi of Liver Cancer Cells Induced by Human LAK Cells
- Tet、DRL和DNR单独应用对K562/A02细胞bcr/ablmRNA及蛋白表达均无影响;The application of single drug of Tet or DRL has no effect on bcr/abl mRNA and BCR/ABL protein expression in K562/A02 cell line.
- T24细胞株T24 Cell lines
- Tet和DRL联合应用于48h开始下调K562/A02细胞bcr/abl mRNA表达,于72h开始下调K562/A02细胞P~(210) BCR/ABL蛋白表达;However,Tet in combination with DRL begins to downregulate bcr/abl mRNA and P~(210) BCR/ABL expression of K562/A02 cells at 48h and 72h respectively.
- NB4细胞株NB4 cell line
- 肝细胞株hepatocyte lines
- FCM检测K562细胞、雷洛昔芬(2.5mg/L)及CsA( 1mg/L)单独及联合作用于K562/A02细胞一定时间细胞内DNR浓度。Pretreating K562/A02 cells with raloxifene(2.5mg/L)or CsA( 1mg/L) for 48 hours partially restored the sensitivity of K562/A02 cells to DNR (IC50 were5.98mg/L and 8.15mg/L respectively) but had no effect on K562 cells;
- A20细胞株A20 cell line
- B9细胞株B9 cell line
- 采用流式细胞仪(FCM)检测K562细胞、雷洛昔芬(2.5mg/L)及CsA( 1mg/L)单独及联合作用于K562/A02细胞一定时间细胞膜上P-gp的表达。and p-glycoprotein expression was detected by fluorometry . Results: The IC50 of DNR for K562/A02 and K562 cells were 23.51mg/L and0.29mg/L respectively.
- CEM细胞株CEM cell line
- CHO细胞株CHO cell