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- Kallikrein is a kind of endopeptidase. 激肽释放酶是一种内切蛋白酶。
- Another example was the alterations seen in kallikrein proteolysis.Dr. 另一个例子则是在微血管增渗酶蛋白质分解中所看到的改变;
- The human tissue kallikrein is a subgroup of serine proteinase family wich contains 15 genes. 人组织型激肽释放酶基因家族(kallikreins,KLK)是丝氨酸蛋白酶家族的一个亚群。
- The kallikrein system, which produces the potent vasodilator bradykinin, is beginning to be studied. 血管舒缓素系统产生强力的血管扩张物质缓激肽,有人正开始这种研究。
- Through the preliminary optimization of the purification condition, we got high purity of pancreas kallikrein product. 通过纯化条件的初步优化,最终得到胰K纯品,收率大于85%25。
- In this paper, we describe the structure, quality, enzyme assay, preparation and clinical practice of kallikrein. 本文概述了激肽释放酶的结构、性质、活力测定、制备及临床应用等内容。
- Fluorescent labeled PTD-kallikrein and Kallikrein were incubated with different types of cells. 将荧光标记的PTD-kallikrein及Kallikrein分别孵育不同细胞,在荧光显微镜下观察两种荧光物质对生物膜的通透能力。
- Objective:To explore the possibility of the simultaneous extraction of urokinase and kallikrein. 目的:探讨尿激酶及激肽释放酶同时提取的可能性。
- It was presumed that KBP may playa role in the regulation of metabolism of tissue kallikrein on the level of biosynthesis and excretion. 推测KBP可能在合成和分泌的水平上,对组织激肽释放酶的代谢及活性起调节作用。
- After screening, one interesting gene was found, human kallikrein 8 (KLK8), a member of human tissue kallikrein gene family. 经过筛选后,发现一个有趣的基因-人类第八号激肽释放酶,它是属于人类组织激肽释放酶基因家族中的一员。
- The purified KBP and human tissue kallikrein forms a 92 KDa SDS- and heat-stable complex. The complex formation is inhibited by the antibody in a dose dependent manner. 纯化的KBP特异地和~(125)I-HUK结合成92KDa的复合物,复合物的形成具有明显的特异性,KBP不能和前激肽释放酶结合。
- OSCS-containing heparin and synthetically derived OSCS induced hypotension associated with kallikrein activation when administered by intravenous infusion in swine. 在猪上静脉用OSCS污染的肝素和合成的OSCS后,能使激肽释放酶激活,血压下降。
- It inhibits above all plasmin, kallikrein, trypsin, chymotrypsin and urokinase but not carboxypeptidase A and B, papain, pepsin, subtilisin, thrombin and factor X. 抑制所有的纤维蛋白溶酶、激肽释放酶、胰蛋白酶、胰凝乳蛋白酶和尿激酶,但不包括羧肽酶A和B、木瓜蛋白酶、胃蛋白酶、枯草菌蛋白酶、凝血酶和X因子。
- The average yield and enzyme activity extracted by SP resin were compared with those by 113 resin, J_2 resin and Amberlite CG50. The experiment showed that kallikrein in the mother solution in which elastase had been removed by SP resin could be prepared. 同时还将SP树脂与国内生产弹性酶的J_2树脂、113树脂及Amberlite CG50进行了比较。 实验结果表明:利用SP树脂吸附弹性酶后的母液仍可回收胰激肽释放酶。
- Objective To investigate the effect of recombinant aden o-associated virus vector(AVV) expressing the human tissue kallikrein(HK)ge ne (rAVV/HK) on human umbilical vein endothelial cells(HUVECs) in vitro. 目的 探讨重组人组织型激肽释放酶 (HK)基因腺相关病毒载体 (rAVV/HK)对体外培养的人脐静脉内皮细胞 (HUVECs)作用。
- The purification of kallikrein using CTAB/hexanol/octane reverse micelles extraction has been studied and optimized,under various aqueous pH values, ionic strength and species, CTAB concentration and co-surfactant concentration. 研究了用十六烷基三甲基溴化铵(CTAB)/正己醇/正辛烷反胶束溶液萃取和反萃取商业用胰激肽原酶时,水相pH值、离子强度和种类、CTAB浓度和助表面活性剂浓度等因素对分离效率的影响,并从反胶束微观结构给予解释。
- The accumulated bicarbonate in the vitreous causes increasingly alkaline conditions that precede activation of the kallikrein pathway, a component of the innate inflammatory response. 玻璃体内累积的碳酸盐导致内环境不断碱化,进而激活了激肽释放酶通路,这一通路是炎症反应的组成部分。
- Lab research and clinical application of cerebral ischemia from recent years implied that one member of KKS---Tissue kallikrein (TK) has identified protective effects on ischemic brain tissues. KKS系统中主要成分之一激肽释放酶又可分为组织型和血浆型两类。
- The purification of kallikrein was improved by means of macro-porous anion-exchange resin.The purified product had specific activity 6 timeshigher than the crude one.The purification recovery was 90%. 应用国产大孔型强碱性阴离子交换树脂纯化激肽释放酶,精制回收率为90%25,精品平均比活力比粗品提高6倍,比有机溶剂沉淀法为优。
- Keywords brain ischemia;kallikrein;bradykinin; 脑缺血;激肽释放酶;缓激肽;