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- The tyrosine phosphorylation of leptin receptor was revealed by immuno precipitation. 应用免疫沉淀法检测瘦素受体的酪氨酸磷酸化程度。
- MEKK2 also synergized with anti-CD3 antibody to activate JNK in T cells, and stimulation of T cells led to induction of MEKK2 tyrosine phosphorylation. MEKK2也是JNK的强烈激活物，能激活JNK依赖的AP-1和IL-2报告基因表达。 当用抗CD28抗体刺激时MEKK2介导的JNK活性无变化，而随着抗CD3抗体刺激，MEKK2介导的JNK活性显著增加。
- Conclusion： Human UREB1 may be involved in the development of tumor and its tyrosine phosphorylation may affect the degree of tumor malignant. 结论：UREB1可能参与肿瘤的发生发展，其酪氨酸磷酸化水平可以影响肿瘤的恶性程度。
- Objective To investigate effects of leptin on gene and protein expression and tyrosine phosphorylation of leptin receptor in rat hepatocytes. 目的观察瘦素对大鼠肝细胞瘦素受体蛋白、基因表达及酪氨酸磷酸化的影响。
- We used immunoprecipitation and Western Blotting assay to examine PTK-mediated tyrosine phosphorylation induced by TPO in Mo7e/TPO. 通过免疫沉淀和免疫印迹试验研究TPO诱导的Mo7e/TPO细胞内PTK介导的酪氨酸磷酸化状态；
- Objective The study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells. 目的研究胃泌素对人结肠癌细胞信号分子黏着斑激酶(FAK)酪氨酸磷酸化和蛋白质表达的影响。
- The results showed that CCL4and HG inhibited the GK activity,elevated Caconcen tration and decreased the level of tyrosine phosphorylation in hepatocytes. 实验结果表明;CCL4和HG均使肝细胞内葡萄糖激酶活性下降;Ca超载;并使细胞内酪氨酸磷酸化水平降低.
- After treatment of MNC of CML and K562 with imatinib in vitro, the expression of DNA-PKcs protein was enhanced while tyrosine phosphorylation of bcr-abl fusion protein decreased. 伊马替尼体外作用于CML患者MNC及K562细胞后,DNA-PKcs蛋白表达量随着bcr-abl融合蛋白酪氨酸磷酸化水平的降低而升高。
- Through b ind ing to its receptor,TPO can induce receptor d im eriza-tion and tyrosine phosphorylation,and then activate a series of signaling pathways,inc lud ing JAK /STAT,Shc /Ras/MAPK and PI3K /Akt. TPO与其受体c-Mp l结合后,c-Mp l形成同源二聚体,激活JAK/STAT、Shc/Ras/MAPK、PI3K/Akt等信号通路,引发一系列生理效应。
- After treatment with imatinib in mononuclear cell (MNC) of CML patients and K562 in vitro, expression of DNA-PKcs mRNA was detected by RT-PCR and DNA-PKcs protein level, tyrosine phosphorylation of bcr-abl fusion protein were detected by Western blot. 用伊马替尼体外作用CML患者的单个核细胞(MNC)及K562细胞后,用RT-PCR、Western blot方法分别检测DNA-PKcs mRNA和DNA-PKcs蛋白表达及bcr-abl融合蛋白的酪氨酸磷酸化水平。
- Tyrosine phosphorylation inhibitor 酪氨酸磷酸化抑制剂
- protein tyrosine phosphorylation 蛋白酪氨酸磷酸化
- SLM-1 is an RNA-binding protein that is tyrosine phosphorylated by Src during mitosis. 类Sam68哺乳动物蛋白1（SLM-1）， 是一个RNA结合蛋白，在有丝分裂中被Src酪氨酸磷酸化。
- Keywords focal adhesion kinase;tyrosine phosphorylation;cells size; 黏着斑激酶;酪氨酸磷酸化;细胞大小;
- Effects of free fatty acid on gene expression and protein tyrosine phosphorylation of leptin-receptor in rats 游离脂肪酸对大鼠瘦素受体基因表达及蛋白酪氨酸磷酸化的影响
- Role of c-met tyrosine phosphorylation on hepatic regeneration and its correlative mechanisms after partial hepatectomy 肝切除诱导c-met受体酪氨酸磷酸化及组织再生的调控机制
- Focal adhesion kinase tyrosine phosphorylation promotes rat hepatic fibrogenesis and its possible mechanism 黏着斑激酶酪氨酸磷酸化促大鼠肝纤维化形成及其可能机制
- Current in guinea pig ventricular myocytes treated with modulators of tyrosine phosphorylation 酪氨酸磷酸化调节剂对豚鼠心室肌细胞
- Effects of As_2O_3 on the BCR/ABL protein tyrosine phosphorylation in K562 cells As_2O_3对K562细胞BCR/ABL蛋白酪氨酸磷酸化的影响
- Effects of Tyrosine Phosphorylation of Focal Adhesion Kinase on Stretch-dependent Cell Morphological Changes 黏着斑激酶酪氨酸磷酸化在牵拉依赖的细胞形态改变中的作用
