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- Preliminary data indicate that steviol may be activated to a mutagenic metabloite by human liver microsomes. 初步数据显示,甜菊醇可能经人体的肝脏微粒体活化成引致基因突变的代谢物。
- Based on metabolite analysis, several PAC-1 metabolic pathways in human liver microsomes were proposed. 结论 PAC-1在人肝微粒体系中的代谢途径为脱苄基化和羟基化。
- Preparation of monoclonal antibody against human liver microsome proteins 抗人肝微粒体蛋白单克隆抗体细胞系的建立及鉴定
- The mean (MEGX+GX)/LDC ratio was 3 2 8. CONCLUSIONThe (MEGX+GX)/LDC ratio can be used to evaluate C YP3A activity of human liver microsomes. 结论 (MEGX +GX) /LDC可用来估算人肝微粒体CYP3A的活性。
- Human liver kidney microsome autoantibody，LKM ... 人抗肝肾微粒体抗体（LKM）试剂盒；
- AIM A HPLC method for the determination of cilnidipine and its major metabolite was developed and the kinetics of its metabolism in human liver microsomes was studied. 目的建立人肝微粒体中西尼地平及其脱氢代谢物的HPLC测定法,并用本法研究西尼地平在人肝微粒体中代谢的动力学。
- Study on activity level and kinetics characteristic of human liver microsome ethylmorphine N-demethylase 成人肝细胞微粒体乙基吗啡N-脱甲基酶活性及酶动力学研究
- Methods In this study, a liquid chromatography-time of flight mass spectrometric method was developed and applied to characterize the metabolites of PAC-1 after incubation with human liver microsomes. 方法 在一定的人肝微粒体浓度中加入药物，温孵后，采用液相色谱-飞行时间质谱法对孵化体系中的代谢产物进行分析。
- Keywords daidzein;human liver microsome;hydroxylation metabolism;cytochrome P450 （CYP1A2）; 大豆苷元;人肝微粒体;羟基化代谢;细胞色素P450（CYP1A2）;
- IN VITRO METABOLIC STUDIES OF THE NOVEL ANTI-ANXIETIC DRUG AF-5 AND ITS METABOLITES IN HUMAN LIVER MICROSOME INCUBATION SYSTEM 抗焦虑新药AF-5及其代谢物在人肝微粒体体外温孵体系中代谢研究
- DETERMINATION OF NIMODIPINE AND ITS DEHYDROGENATION METABOLITE IN HUMAN LIVER MICROSOME BY HPLC AND ITS METABOLIZING KINETICS 人肝微粒体中尼莫地平及其脱氢代谢物的HPLC测定法及代谢动力学
- human liver microsome 人肝微粒体
- human liver microsome proteins 人肝微粒体蛋白
- In this study, we investigated its metabolism by use of rat liver microsome in vitro. 利用大鼠肝微粒体对新农药多噻烷进行体外代谢研究。
- The Bradford method was used to measure the concentration of protein in liver microsome, and activities of cytochrome P450 enzymes were determined by the spectrophotometer method. 测定一月龄至八月龄不同性别的猪，肝微粒体蛋白含量、CYP450含量、CYPb5含量、NADPH-细胞色素C还原酶活性、氨基比林-N-脱甲基酶活性、红霉素-N-脱甲基酶活性和苯胺-4-羟化酶活性。
- And it can induce human liver cancer,carcinoma of tesis esophagus cancer. 目前的检测方法有:高效液相色谱、气相色谱、薄层色谱、无毒检测体系和免疫学检测。
- Antioxidant activities of extractions were determined by chemical methods to produce superoxide free radicals, hydroxide free radicals and lipid peroxide of rat liver microsome. 采用化学方法产生超氧阴离子自由基、羟自由基和小鼠肝匀浆液脂质过氧化体系对提取物进行抗氧化活性检测,研究其清除自由基和抑制脂质过氧化能力的差异。
- The proper conditions for testotesrone metabolism in liver microsome system included substrate concentration, incubation time, pH and incubation temperature. 方法：采用超高速离心法制备大鼠肝脏微粒体，建立体外肝脏微粒体混合酶代谢体系。
- According to recent materials,Introduce liver microsome incubations in vitro,liver cell incubations in vitro,isolated perfused liver and liver slices,respectively. 对近几年的文献资料进行分析、综合、归纳。
- Previous studies have identified CYP1 A2 and CYP3A4 as the major enzymes for AFB_1 activation in human liver. 但由于CYP1A2主要在肝脏中表达，而在肺脏中甚微，因而至今还不清楚在人肺脏中究竟哪些CYPs在AFB1的代谢活化中发挥关键性的作用。
