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- Objective To st,udy the effects of 2-APB on store operated calcium current (Isoc) in isolated rat hepatocytes. 目的探讨钙池操纵的钙通道(SOC)抑制剂(2APB)对大鼠肝细胞SOC电流(Isoc)的影响。 方法急性分离大鼠肝细胞,应用全细胞膜片钳记录技术测定大鼠肝细胞Isoc,并观察2APB对该电流的影响。
- Objective This paper is to study the mechanism of HI 6,PAM Cl,PAM I and obidoxime against the inhibition of DDVP on isolated rat phrenic diaphragm. 目的研究HI-6、PAM-Cl、PAM-I和双复磷等肟类药物对抗敌敌畏抑制离体大鼠膈肌的作用机制。
- Noradrenaline decreased I_(K) distincily.Isoprenaline and acetylcholine showed no effect on I_(K) in isolated rat hepatocytes. 去甲肾上腺素明显降低I_(K),异丙肾上腺素和乙酰胆碱对I_(K)无影响。
- Second, in isolated rat adipose cells, glucose transporter 4 trafficking can be visualized by transfection of HA-GLUT4-GFP. 然后,在大鼠的脂肪细胞中,通过转染HA-GLUT4-GFP来观察葡萄糖转运蛋白4的转运过程。
- Objective To explore the protective effects of WIN55212-2,an agonist of cannabinoid receptor,on ischemia-reperfusion injury in isolated rat hearts. 目的探讨大麻素受体激动剂WIN55212-2对体外大鼠心肌缺血再灌注损伤的保护作用。
- Objective To study and compare the effect of shuichandpu and shichangpu on contractile of isolated rat gastric muscle strips. 目的:观察水菖蒲和石菖蒲对大鼠离体胃平滑肌条运动的影响,并比较二者作用的异同。
- METHODS: Cell membrane of isolated rat pancreatic acini were permeabilized using streptolysin O (SLO). Enzymes secretions were indicated by detecting total protein secretions. 方法:分离大鼠胰腺腺泡细胞,用链球菌溶血素-O(SLO)通透细胞膜,检测腺泡分泌蛋白量标志腺泡酶分泌功能。
- Featherstone RL, Chambers DJ, Kelly FJ. Ischemic-preconditioning enhances recovery of isolated rat lungs after hypothermic preservation [J]. Ann Thorac Surg, 2000(1): 237. 李建华;司志萍,卢佳怡,等.;缺血预处理对大鼠肺缺血/再灌注损伤的保护作用[J]
- Objective To observe the delayed protective effects of ramipril on myocardial ischemic-reperfusion injury in isolated rat hearts and explore the possible mechanisms. 目的探讨雷米普利预适应对大鼠离体心脏缺血-再灌注损伤的延迟性保护作用及机制。
- Objective:To evaluate the protective effects of low-flow preconditioning before hypothermic cardioplegic arrest on isolated rat working heart subjected to 120 minutes of ischemia. 目的:探讨低流量预适应对缺血心肌的保护作用。
- Objective To study the delayed protective effects of norepinephrine preconditioning by express-ing heat shock protein70(HSP70)on reperfused myocardium in isolated rat heart. 目的观察去甲肾上腺素预处理后热休克蛋白(HSP70)在心肌细胞的表达以研究去甲肾上腺素预处理对大鼠离体缺血再灌注损伤心肌的延迟性保护作用。
- The functional roles of the NaChs were tested by observing the effect of tetrodotoxin, a specific blocker of NaChs, on the intrinsic heart rate of isolated rat working heart. 建立大鼠离体灌流心脏模型,观察钠通道特异性阻断剂河豚毒素对离体灌流心脏自发性节律即固有心率的影响。
- Objective:Our purpose was to study the influence of KATP channel opener KRN2391(KRN) on cardiac function and myocardial infarct size of isolated rat heart. 目的:探讨ATP敏感性钾通道(KATP通道)开放剂KRN2391(KRN)对离体大鼠心功能及心肌梗死范围的影响。
- AIM To study if there are different effects of 9 enantiomers of clausenamides on aflatoxin B_1(AFB_1)-induced unscheduled DNA synthesis(UDS) injury and glutamic-pyruvic transferase(GPT) release of isolated rat hepatocytes in vitro. 目的研究9种光学活性黄皮酰胺类化合物体外对黄曲霉毒素B1(AFB1)引起大鼠肝细胞非程序性DNA合成(UDS)损伤和谷丙转氨酶(GPT)释放的保护作用有无差异。
- METHODS The isolated rat intestinal membranes were used to study the effects of Labrasol on the transportation of Rhodamine123(a subtrate of P-gp) and Lucifer yellow(non-subtrate of P-gp )by ussing chamber. 方法 用大鼠的离体肠段,通过体外Ussingchamber的转运实验,研究了Labrasol对P -糖蛋白底物若丹明1 2 3转运的影响,同时考察了非P -糖蛋白底物荧光黄在Labrasol作用下的转运行为。
- METHODS: Local field stimulation was delivered to freshly isolated rat single cardiac myocytes to generate action-potential-induced Ca 2+ transients (ACT) for assessing intracellular Ca 2+ release. 方法 :局部场刺激作用于成年大鼠心肌细胞 ,促使后者产生动作电位 ,进而诱发胞内钙瞬变 (ACT) ,由 ACT可估测胞内钙释放。
- The inhibitory effect of the extract from SGY on contractility of isolated rat colonic smooth muscle strips may be associated with blocking VDC,ROC and SOC to prevent the calcium influx as well as to prevent the release of intracellular calcium. 疏肝饮具有抑制大鼠结肠平滑肌收缩的作用,机制可能涉及通过阻断电压门控钙通道(VDC)、受体操纵性钙通道(ROC)和钙库调控性钙通道(SOC)抑制胞外Ca2+内流,同时涉及抑制胞内Ca2+的释放。
- Results: Fructus corni has effect as follows: dramatric postive inotropic effect on the isolated rat s left ventricular papillary;Obvious effect of strengthing the left ventricular fu... 结果:山茱萸能明显增强大鼠离体乳头肌收缩强度,改善家兔左室功能,为前人的用药经验提供了现代药理学基础。
- METHODS: The calcium content of the myocardium, lactate dehydrogenase (LDH) release, protein loss and coronary flow were measured after the isolated rat hearts were perfused by TFP and VP. 方法:应用TFP与VP对离体大鼠心脏进行灌流。检测心肌钙含量、灌流液中乳酸脱氢酶(LDH)及心肌蛋白漏出量等指标。
- Objective To study changes in electrophysiological characteristics of muscle spindles induced by simulated weightlessness in isolated rats soleus. 目的观察模拟失重不同时期大鼠离体比目鱼肌肌梭电生理特性的改变。