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- MyD88 is a critical component in the signaling cascade through Toll-like receptors, interleukin-1 and interleukin-18 receptors. 目前已知,MyD88蛋白是 Toll样受体、白介素-1受体、白介素-18受体介导的信号通路中的关键分子,由它参与构成的信号级联最终引起核因子kappa B(Nuclear factor-kappa B,NF-kB)依赖性信号通路的活化。
- Of three factors (1-methyl-3-isobutylxanthine,dexamethasone and insulin) inducing 3T3-L1 preadipocyte differentiation,only insulin was able to activate the PI3K-Akt signal cascade. 在三个诱导 3T3-L1 前脂肪细胞分化的激素(1-甲基-3-异丁基次黄嘌呤、地塞米松和胰岛素)中,只有胰岛素能激活 PI3K-Akt 信号通路。
- Two signaling cascades had emerged as major players in the AngII-induced vascular endothelial cell proliferation: the PI3K-p70 S6K cascade and the Ras-p42/p44 MAPK cascade. 结论:(1)慢性CsA肾病肾移植患者肾组织局部RAS活化,CsA刺激血管内皮细胞分泌AngII,蛋白质合成增加。(2)AngII刺激血管内皮细胞蛋白质合成增加通过激活PI3K-p70 S6K和Ras-p42/p44 MAPK两条信号通路。
- AIM: To study the role of adaptor protein Bam32 in B cell antigen receptor (BCR) signaling cascades. 目的:研究接头蛋白(adaptorprotein)Bam32在B细胞抗原受体(Bcellantigenreceptor,BCR)信号转导级联反应中的作用。
- The molecule appeared to initiate some signaling cascades that could affect inappropriately proliferating cells but not normal ones. 分子显示出能引发一些信号级联,可能影响到不适当增殖的细胞,但不作用于正常细胞。
- Similarly, the constitutive activation of signaling cascades that stimulate cell growth has a profound impact on anabolic metabolism. 类似的,刺激细胞生长组成性激活的信号传递对同化代谢具有重大的影响。
- The initial formation of the polarized state involves signaling cascades that epithelial cells use to orient themselves to sites of cell-cell and cell-matrix contact. 上皮细胞通过细胞信号转导途径形成极化初始状态,将自己定位于特定位置,调节细胞与细胞之间、细胞与基质之间的相互作用。
- The activation of PTK/transcription activator signaling cascades can stimulate the excessive proliferation of mesangial cell proliferation and then result in diabetic nephropathy. 蛋白酪氨酸激酶/转录激活子途径信号级联放大的激活刺激肾小球膜细胞过度增殖,导致糖尿病肾病。
- peroxisome proliferators γ activated receptor coativator-1α signaling cascade 过氧化物酶体增殖物激活受体γ辅激活因子级联
- Summary of Background Data.With current in io models for the study of disc and endplate degeneration, it remains difficult to inestigate the complex disc metabolism and signaling cascades. 背景数据的总结:目前在研究椎间盘和终板退化的体内模型中,观察复杂的椎间盘的代谢过程和信号级联放大过程是很困难的。
- A red light is usually a signal of danger. 红灯通常是危险的信号。
- His human heart in its cage of bone echoed the beat of an alien one in a casket of armorplast, and his mind whirred with the electronic signal cascades that passed for thought in Jedi-killer droids. 他那个在骨头环绕下的人类心脏搏动着一个被塑甲棺材所覆盖的异族的心律节奏,而他的心灵则与那位绝地杀手机器人的电子信号一同飞旋。
- I stood watching for the signal to change to green. 我站着等待交通信号转为绿灯。
- Let's set the clock by the radio time signal. 咱们照着收音机的报时信号把钟对一对。
- A red lamp is often a danger signal. 红灯常常是危险的信号。
- ROS induce programmed cell death or necrosis, induce or suppress the expression of many genes, and activate cell signalling cascades, such as those involving. 活性氧可以诱导细胞程序性死亡或坏死、可以诱导或抑制许多基因的表达,也可以激活上述级联信号。
- A reflected signal on a communication channel. 一种在通信信道上反射回来的信号。
- The rise in prices was a signal for rebellion. 物价上涨引起了叛乱。
- A channel over which pilot signal is transmitted. 可在其上传输导频信号的一种信道。
- The signal was picked up by a downrange radar station. 该信号被试验飞行方向之内的雷达站收到了。