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- FCM检测K562细胞、雷洛昔芬(2.5mg/L)及CsA( 1mg/L)单独及联合作用于K562/A02细胞一定时间细胞内DNR浓度。Pretreating K562/A02 cells with raloxifene(2.5mg/L)or CsA( 1mg/L) for 48 hours partially restored the sensitivity of K562/A02 cells to DNR (IC50 were5.98mg/L and 8.15mg/L respectively) but had no effect on K562 cells;
- 采用流式细胞仪(FCM)检测K562细胞、雷洛昔芬(2.5mg/L)及CsA( 1mg/L)单独及联合作用于K562/A02细胞一定时间细胞膜上P-gp的表达。and p-glycoprotein expression was detected by fluorometry . Results: The IC50 of DNR for K562/A02 and K562 cells were 23.51mg/L and0.29mg/L respectively.
- K562/A02细胞K562/A02 cell
- 细胞cell
- K562／A02细胞株K562/A02 cell line
- 细胞的cellular
- K562／A02细胞K562/A02 cell
- 经肝脏微粒体酶代谢后,FM01、Cur抑制K562细胞株生长活性均呈下降趋势。Both inhibitory activity of FM01 and Cur on K562 cells took decrease tendency after treated with microsomal mixed-function oxidase.
- K562细胞／A02细胞K562 cell/A02 cell
- K562细胞株K562 cell line
- BCR/ABL特异性siRNA真核表达载体构建及其对K562细胞的影响Construction of Eukaryotic Expression Vector of SiRNA Specific for BCR/ABL Fusion Gene and Its Effects on K562 Cells
- 汉防己甲素联合屈洛昔芬对K562/A02细胞bcr/abl表达的影响Effect of Tetrandrine in Combination With Droloxifen on the Expression of bcr/abl mRNA and Protein of K562/A02
- 切割bcr/abl核酶的逆转录病毒载体构建及其对K562细胞的影响Construction of retrovirus vector of bcr/abl mRNA cleaving ribozyme gene and its effects on K562 cells
- 在BCR/ABL基因组上敲入mRNA不稳定元件可逆转K562细胞恶性转化Reversing Malignant Transformation of K562 Cells by Knock in an RNA Destabilizing Element into BCR/ABL Genome
- 转导野生型p53基因提高K562细胞对紫外线诱导的细胞凋亡的敏感性Enhancement of apoptotic sensitivity induced by UV irradiation on the p53 transducted K562 cells
- Tet、DRL和DNR单独应用对K562/A02细胞bcr/ablmRNA及蛋白表达均无影响;The application of single drug of Tet or DRL has no effect on bcr/abl mRNA and BCR/ABL protein expression in K562/A02 cell line.
- As_2S_2与STI 571协同诱导K562细胞凋亡Synergism of As_2S_2 and STI 571 in inducing apoptosis of K562 cells
- 白藜芦醇联合阿糖胞苷对K562细胞的影响The Inhibition of Resveratrol in Combination with Ara-C on Human Leukemia K562 Cell
- Tet和DRL联合应用于48h开始下调K562/A02细胞bcr/abl mRNA表达,于72h开始下调K562/A02细胞P~(210) BCR/ABL蛋白表达;However,Tet in combination with DRL begins to downregulate bcr/abl mRNA and P~(210) BCR/ABL expression of K562/A02 cells at 48h and 72h respectively.
- 联合应用bcr-abl融合基因反义寡核苷酸与c-myb基因反义寡核苷酸对K562细胞作用的研究The Effect of Combining bcr-abl Antisense Phosphorothioate Oligodeoxynucleotides and c-myb Aspo on K562 Cell Line
